Menstrual blood loss and fibrin degradation products.
نویسندگان
چکیده
As part of a large-scale study of menstrual blood loss in the community serum fibrin degradation products were measured soon after menstruation in 331 women. No significant correlation was found between the amount of blood lost and the serum level of fibrin degradation products. These findings conflict with reports suggesting that excessive intrauterine fibrinolysis, which may play a part in menorrhagia, is associated with raised serum F.D.P. concentrations.
منابع مشابه
Fibrin degradation products in sera of women with normal menstruation and menorrhagia.
Serum concentrations of fibrin degradation products were found to be higher during menstruation than in the intermenstrual phase. Higher concentrations were present in cases of menorrhagia as compared with healthy women and women with various gynaecological disorders but with normal menstrual function. Higher serum concentrations of fibrin degradation products in cases of menorrhagia may indica...
متن کاملClinical applications of fibrinolytic inhibition in gynaecology.
'In healthy menstruation the blood which is discharged does not coagulate; in the irregular or unhealthy it does....' This observation on the non-coagulability of menstrual blood was made by John Hunter in 1794.1 A similar observation was made by Bell in 19122 on the composition of menstrual blood found in patients with haematocolpos. Over the past 20 years laboratory and clinical research has ...
متن کاملHow can fibrinolysis induce cell death?
In this issue of Blood, Guo and colleagues elucidate molecular details of a novel mechanism, linking the degradation of fibrin (but not fibrinogen) by plasmin to apoptosis of placental trophoblast cells. There is convincing evidence from the literature that disorders of the maternal coagulation system are associated with complications of pregnancy including fetal loss. In many studies, an assoc...
متن کاملThe role of fibrinogen, fibrin and fibrin(ogen) degradation products (FDPs) in tumor progression
Participation of fibrin, fibrinogen, and their degradation products in pathogenesis and progression of cancer may lead to complications of thromboembolic events. The tumor may be a source of fibrinogen. Fibrinogen inside the tumor is one of the factors of its growth and metastasis. Fibrinogen, fibrin and their degradation products possess proinflammatory activity. They indirectly stimulate endo...
متن کاملTranexamic acid in paediatric cardiac surgery.
BACKGROUND & OBJECTIVES Antifibrinolytic agents are used commonly in adult cardiac surgery to reduce postoperative blood loss. Paucity of literature on the use of a newer antifibrinolytic agent tranexamic acid (TA) in children undergoing cardiac surgery promoted us to conduct this study in children with cyanotic heart disease. METHODS One hundred and twenty consecutive children with cyanotic ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- British medical journal
دوره 1 5792 شماره
صفحات -
تاریخ انتشار 1972